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TGF-β concentrations and activity are down-regulated in the aqueous humor of patients with neovascular age-related macular degeneration

Controversy still exists regarding the role of the TGF-β in neovascular age-related macular degeneration (nAMD), a major cause of severe visual loss in the elderly in developed countries. Here, we measured the concentrations of active TGF-β1, TGF-β2, and TGF-β3 by ELISA in the aqueous humor of 20 pa...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Tosi, Gian Marco, Neri, Giovanni, Caldi, Elena, Fusco, Fiorella, Bacci, Tommaso, Tarantello, Antonio, Nuti, Elisabetta, Marigliani, Davide, Baiocchi, Stefano, Traversi, Claudio, Barbarino, Marcella, Eandi, Chiara M., Parolini, Barbara, Mundo, Lucia, Santucci, Annalisa, Orlandini, Maurizio, Galvagni, Federico
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966430/
https://ncbi.nlm.nih.gov/pubmed/29795291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26442-0
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