TGF-β concentrations and activity are down-regulated in the aqueous humor of patients with neovascular age-related macular degeneration

Controversy still exists regarding the role of the TGF-β in neovascular age-related macular degeneration (nAMD), a major cause of severe visual loss in the elderly in developed countries. Here, we measured the concentrations of active TGF-β1, TGF-β2, and TGF-β3 by ELISA in the aqueous humor of 20 pa...

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Publicado en:Sci Rep
Main Authors: Tosi, Gian Marco, Neri, Giovanni, Caldi, Elena, Fusco, Fiorella, Bacci, Tommaso, Tarantello, Antonio, Nuti, Elisabetta, Marigliani, Davide, Baiocchi, Stefano, Traversi, Claudio, Barbarino, Marcella, Eandi, Chiara M., Parolini, Barbara, Mundo, Lucia, Santucci, Annalisa, Orlandini, Maurizio, Galvagni, Federico
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966430/
https://ncbi.nlm.nih.gov/pubmed/29795291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26442-0
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