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Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons

Despite critical roles of the hypothalamic arcuate neurons in controlling the growth and energy homeostasis, the gene regulatory network directing their development remains unclear. Here we report that the transcription factors Dlx1/2 and Otp coordinate the balanced generation of the two functionall...

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Foilsithe in:Nat Commun
Main Authors: Lee, Bora, Kim, Janghyun, An, Taekyeong, Kim, Sangsoo, Patel, Esha M., Raber, Jacob, Lee, Soo-Kyung, Lee, Seunghee, Lee, Jae W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966420/
https://ncbi.nlm.nih.gov/pubmed/29795232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04377-4
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