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Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons

Despite critical roles of the hypothalamic arcuate neurons in controlling the growth and energy homeostasis, the gene regulatory network directing their development remains unclear. Here we report that the transcription factors Dlx1/2 and Otp coordinate the balanced generation of the two functionall...

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Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Lee, Bora, Kim, Janghyun, An, Taekyeong, Kim, Sangsoo, Patel, Esha M., Raber, Jacob, Lee, Soo-Kyung, Lee, Seunghee, Lee, Jae W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966420/
https://ncbi.nlm.nih.gov/pubmed/29795232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04377-4
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