Concentration-dependent protein loading of extracellular vesicles released by Histoplasma capsulatum after antibody treatment and its modulatory action upon macrophages

Diverse pathogenic fungi secrete extracellular vesicles (EV) that contain macromolecules, including virulence factors that can modulate the host immune response. We recently demonstrated that the binding of monoclonal antibodies (mAb) modulates how Histoplasma capsulatum load and releases its extrac...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Baltazar, Ludmila Matos, Zamith-Miranda, Daniel, Burnet, Meagan C., Choi, Hyungwon, Nimrichter, Leonardo, Nakayasu, Ernesto S., Nosanchuk, Joshua D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966397/
https://ncbi.nlm.nih.gov/pubmed/29795301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25665-5
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