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Concentration-dependent protein loading of extracellular vesicles released by Histoplasma capsulatum after antibody treatment and its modulatory action upon macrophages

Diverse pathogenic fungi secrete extracellular vesicles (EV) that contain macromolecules, including virulence factors that can modulate the host immune response. We recently demonstrated that the binding of monoclonal antibodies (mAb) modulates how Histoplasma capsulatum load and releases its extrac...

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Publicado en:Sci Rep
Main Authors: Baltazar, Ludmila Matos, Zamith-Miranda, Daniel, Burnet, Meagan C., Choi, Hyungwon, Nimrichter, Leonardo, Nakayasu, Ernesto S., Nosanchuk, Joshua D.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966397/
https://ncbi.nlm.nih.gov/pubmed/29795301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25665-5
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