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Structural study reveals the temperature-dependent conformational flexibility of Tk-PTP, a protein tyrosine phosphatase from Thermococcus kodakaraensis KOD1

Protein tyrosine phosphatases (PTPs) originating from eukaryotes or bacteria have been under intensive structural and biochemical investigation, whereas archaeal PTP proteins have not been investigated extensively; therefore, they are poorly understood. Here, we present the crystal structures of Tk-...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yun, Hye-Yeoung, Lee, Jinhyuk, Kim, Hyunmin, Ryu, Hyojung, Shin, Ho-Chul, Oh, Byung-Ha, Ku, Bonsu, Kim, Seung Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965843/
https://ncbi.nlm.nih.gov/pubmed/29791483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197635
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