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Structural study reveals the temperature-dependent conformational flexibility of Tk-PTP, a protein tyrosine phosphatase from Thermococcus kodakaraensis KOD1

Protein tyrosine phosphatases (PTPs) originating from eukaryotes or bacteria have been under intensive structural and biochemical investigation, whereas archaeal PTP proteins have not been investigated extensively; therefore, they are poorly understood. Here, we present the crystal structures of Tk-...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Yun, Hye-Yeoung, Lee, Jinhyuk, Kim, Hyunmin, Ryu, Hyojung, Shin, Ho-Chul, Oh, Byung-Ha, Ku, Bonsu, Kim, Seung Jun
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965843/
https://ncbi.nlm.nih.gov/pubmed/29791483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197635
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