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Cysteine-Activated Hydrogen Sulfide (H(2)S) Delivery through Caged Carbonyl Sulfide (COS) Donor Motifs

Hydrogen sulfide (H(2)S) is an important biomolecule, and controllable H(2)S donors are needed to investigate H(2)S biological functions. Here we utilize cysteine-mediated addition/cyclization chemistry to unmask an acrylate-functionalized caged thiocarbamate and release carbonyl sulfide (COS), whic...

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Bibliografski detalji
Izdano u:Chem Commun (Camb)
Glavni autori: Zhao, Yu, Steiger, Andrea K., Pluth, Michael D.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965689/
https://ncbi.nlm.nih.gov/pubmed/29701221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cc02428f
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