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Cysteine-Activated Hydrogen Sulfide (H(2)S) Delivery through Caged Carbonyl Sulfide (COS) Donor Motifs

Hydrogen sulfide (H(2)S) is an important biomolecule, and controllable H(2)S donors are needed to investigate H(2)S biological functions. Here we utilize cysteine-mediated addition/cyclization chemistry to unmask an acrylate-functionalized caged thiocarbamate and release carbonyl sulfide (COS), whic...

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Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: Zhao, Yu, Steiger, Andrea K., Pluth, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965689/
https://ncbi.nlm.nih.gov/pubmed/29701221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cc02428f
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