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Protein lipoylation: An evolutionarily conserved metabolic regulator of health and disease

Lipoylation is a rare, but highly conserved lysine posttranslational modification. To date, it is known to occur on only four multimeric metabolic enzymes in mammals, yet these proteins are staples in the core metabolic landscape. The dysregulation of these mitochondrial proteins is linked to a rang...

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Detalhes bibliográficos
Publicado no:Curr Opin Chem Biol
Main Authors: Rowland, Elizabeth A., Snowden, Caroline K., Cristea, Ileana M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965299/
https://ncbi.nlm.nih.gov/pubmed/29169048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2017.11.003
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