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An In Vivo Murine Sciatic Nerve Model of Perineural Invasion

Cancer cells invade nerves through a process termed perineural invasion (PNI), in which cancer cells proliferate and migrate in the nerve microenvironment. This type of invasion is exhibited by a variety of cancer types, and very frequently is found in pancreatic cancer. The microscopic size of nerv...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Vis Exp
Hauptverfasser: Deborde, Sylvie, Yu, Yasong, Marcadis, Andrea, Chen, Chun-Hao, Fan, Ning, Bakst, Richard L., Wong, Richard J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MyJove Corporation 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965264/
https://ncbi.nlm.nih.gov/pubmed/29733315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/56857
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