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Neutralization of CD40 ligand costimulation promotes bone formation and accretion of vertebral bone mass in mice
OBJECTIVE: Immunosuppressive biologics are used in the management of RA and additional immunomodulators are under investigation including modulators of the CD40/CD40 ligand (CD40L) costimulation pathway. Tampering with immune function can have unanticipated skeletal consequences due to disruption of...
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| Publicado en: | Rheumatology (Oxford) |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5965091/ https://ncbi.nlm.nih.gov/pubmed/29522194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/kex525 |
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