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Inhibition of 5α-Reductase in Rat Prostate Reveals Differential Regulation of Androgen-Response Gene Expression by Testosterone and Dihydrotestosterone

The growth and development of some of the male sex accessory organs such as the prostate requires the conversion of testosterone to dihydrotestosterone (DHT) by 5α-reductase. To provide insights into the role of testosterone versus DHT in the prostate, we studied the impact of finasteride, a potent...

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Publicat a:Gene Expr
Autors principals: Dadras, Soheil S., Cai, Xiaoyan, Abasolo, Ibane, Wang, Zhou
Format: Artigo
Idioma:Inglês
Publicat: Cognizant Communication Corporation 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964941/
https://ncbi.nlm.nih.gov/pubmed/11444528
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