Ecto-5′-nucleotidase (CD73) attenuates inflammation after spinal cord injury by promoting macrophages/microglia M2 polarization in mice

BACKGROUND: Immune activation, specifically activation of macrophages and resident microglia, leading to inflammation is a key component in the progression of spinal cord injury (SCI). Macrophages/microglia exist in two states—the classically activated M1 phenotype that confers pro-inflammatory effe...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Xu, Shun, Zhu, Wei, Shao, Minghao, Zhang, Fan, Guo, Ji, Xu, Haocheng, Jiang, Jianyuan, Ma, Xiaosheng, Xia, Xinlei, Zhi, Xiuling, Zhou, Ping, Lu, Feizhou
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964922/
https://ncbi.nlm.nih.gov/pubmed/29788960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1183-8
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