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IV fosphenytoin in obese patients: Dosing strategies, safety, and efficacy

BACKGROUND: Previous studies evaluated the disposition of IV phenytoin loading doses and found that obese patients had increased drug distribution into excess body weight, larger volumes of distribution, and longer half-lives when compared to their nonobese counterparts. We assess the safety and eff...

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Bibliografische gegevens
Gepubliceerd in:Neurol Clin Pract
Hoofdauteurs: Clark, Sarah L., Leloux, Megan R., Dierkhising, Ross A., Cascino, Gregory D., Hocker, Sara E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Lippincott Williams & Wilkins 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964862/
https://ncbi.nlm.nih.gov/pubmed/29849211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/CPJ.0000000000000322
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