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1562. Safety and Efficacy of High-Dose Cefazolin Therapy in Obesity

BACKGROUND: Obesity leads to altered pharmacokinetics through changes in volume of distribution and clearance, which can impact antimicrobial dosing. Although there is data to support higher cefazolin pre-operative dosing for surgical prophylaxis, data evaluating treatment doses of cefazolin in obes...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Simpson, Timothy, Shah, Sneha, Pogue, Jason M, Wu, Janet
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6809175/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz360.1426
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