Positron Emission Tomography Imaging Reveals an Importance of Saturable Liver Uptake Transport for the Pharmacokinetics of Metoclopramide

Positron emission tomography (PET) imaging using [(11)C]metoclopramide, a P-glycoprotein (P-gp) substrate, was used to investigate the contribution of transport processes to metoclopramide liver clearance. The liver kinetics obtained after injection of [(11)C]metoclopramide were measured using PET i...

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Dettagli Bibliografici
Pubblicato in:Contrast Media Mol Imaging
Autori principali: Caillé, Fabien, Goutal, Sébastien, Marie, Solène, Auvity, Sylvain, Cisternino, Salvatore, Kuhnast, Bertrand, Pottier, Géraldine, Tournier, Nicolas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964550/
https://ncbi.nlm.nih.gov/pubmed/29853808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/7310146
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