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The Adjuvant Bordetella Colonization Factor A Attenuates Alum-Induced Th2 Responses and Enhances Bordetella pertussis Clearance from Mouse Lungs

The reemergence of pertussis or whooping cough in several countries highlights the need for better vaccines. Acellular pertussis vaccines (aPV) contain alum as the adjuvant and elicit Th2-biased immune responses that are less effective in protecting against infection than the reactogenic whole-cell...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Jennings-Gee, Jamie, Quataert, Sally, Ganguly, Tridib, D'Agostino, Ralph, Deora, Rajendar, Dubey, Purnima
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964531/
https://ncbi.nlm.nih.gov/pubmed/29531137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00935-17
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