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Tumor Necrosis Factor Alpha Antagonism Reveals a Gut/Lung Axis That Amplifies Regulatory T Cells in a Pulmonary Fungal Infection

Tumor necrosis factor (TNF) antagonists are popular therapies for inflammatory diseases. These agents enhance the numbers and function of regulatory T cells (Tregs), which are important in controlling inflammatory diseases. However, elevated Treg levels increase susceptibility to infections, includi...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Tweedle, Jamie L., Deepe, George S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964519/
https://ncbi.nlm.nih.gov/pubmed/29581197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00109-18
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