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Comparison of Immunogenicity and Protection of Two Pneumococcal Protein Vaccines Based on PsaA and PspA

Streptococcus pneumoniae is a major cause of invasive pneumococcal disease, septicemia, and meningitis that can result in high morbidity rates in children under 5 years old. The current polysaccharide-based vaccines can provide type-specific immunity, but a broad-spectrum vaccine would provide great...

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Yu, Jinfei, Li, Bo, Chen, Xiaorui, Lu, Jingcai, Wang, Dandan, Gu, Tiejun, Kong, Wei, Wu, Yongge
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964518/
https://ncbi.nlm.nih.gov/pubmed/29610257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00916-17
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