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FoxM1-dependent RAD51 and BRCA2 signaling protects idiopathic pulmonary fibrosis fibroblasts from radiation-induced cell death

Radiation therapy is critical for the control of many tumors and lung is an important dose-limiting organ that impacts radiation dose prescribed to avoid irreversible pulmonary fibrosis in cancer survivors. Idiopathic pulmonary fibrosis (IPF) is a chronic, irreversible lung disease caused by aberran...

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Vydáno v:Cell Death Dis
Hlavní autoři: Im, Jintaek, Lawrence, Jessica, Seelig, Davis, Nho, Richard S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964221/
https://ncbi.nlm.nih.gov/pubmed/29789556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0652-4
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