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Inhibiting p38 MAPK alpha rescues axonal retrograde transport defects in a mouse model of ALS
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease caused by the degeneration of upper and lower motor neurons. Defects in axonal transport have been observed pre-symptomatically in the SOD1(G93A) mouse model of ALS, and have been proposed to play a role in motor neuron degener...
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| Publié dans: | Cell Death Dis |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5964181/ https://ncbi.nlm.nih.gov/pubmed/29789529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0624-8 |
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