Efficient Blood-Brain Barrier Opening in Primates with Neuronavigation-Guided Ultrasound and Real-Time Acoustic Mapping

Brain diseases including neurological disorders and tumors remain under treated due to the challenge to access the brain, and blood-brain barrier (BBB) restricting drug delivery which, also profoundly limits the development of pharmacological treatment. Focused ultrasound (FUS) with microbubbles is ...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wu, Shih-Ying, Aurup, Christian, Sanchez, Carlos Sierra, Grondin, Julien, Zheng, Wenlan, Kamimura, Hermes, Ferrera, Vincent P., Konofagou, Elisa E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964111/
https://ncbi.nlm.nih.gov/pubmed/29789530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25904-9
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