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Characterizing Focused-Ultrasound Mediated Drug Delivery to the Heterogeneous Primate Brain In Vivo with Acoustic Monitoring

Focused ultrasound with microbubbles has been used to noninvasively and selectively deliver pharmacological agents across the blood-brain barrier (BBB) for treating brain diseases. Acoustic cavitation monitoring could serve as an on-line tool to assess and control the treatment. While it demonstrate...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wu, Shih-Ying, Sanchez, Carlos Sierra, Samiotaki, Gesthimani, Buch, Amanda, Ferrera, Vincent P., Konofagou, Elisa E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5112571/
https://ncbi.nlm.nih.gov/pubmed/27853267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37094
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