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Celastrol alleviates renal fibrosis by upregulating cannabinoid receptor 2 expression

Renal fibrosis is the final manifestation of various chronic kidney diseases, and no effective therapy is available to prevent or reverse it. Celastrol, a triterpene that derived from traditional Chinese medicine, is a known potent anti-fibrotic agent. However, the underlying mechanisms of action of...

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Bibliografske podrobnosti
izdano v:Cell Death Dis
Main Authors: Tang, Ming, Cao, Xu, Zhang, Kun, Li, You, Zheng, Quan-you, Li, Gui-qing, He, Qian-hui, Li, Shu-jing, Xu, Gui-lian, Zhang, Ke-qin
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964092/
https://ncbi.nlm.nih.gov/pubmed/29789558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0666-y
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