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Genetic risk score is associated with vertical cup-disc ratio and improves prediction of primary open angle glaucoma in Latinos

PURPOSE: Genome-wide association studies have identified multiple genetic variants associated with vertical cup-disc ratio (VCDR). Genetic risk scores (GRS) examine the aggregate genetic effect of individual variants on a trait by combining these separate genetic variants into a single measure. The...

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Publicat a:Ophthalmology
Autors principals: Nannini, Drew R., Kim, Heejin, Fan, Fangda, Gao, Xiaoyi
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963986/
https://ncbi.nlm.nih.gov/pubmed/29361357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ophtha.2017.12.014
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