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Genetic risk score is associated with vertical cup-disc ratio and improves prediction of primary open angle glaucoma in Latinos
PURPOSE: Genome-wide association studies have identified multiple genetic variants associated with vertical cup-disc ratio (VCDR). Genetic risk scores (GRS) examine the aggregate genetic effect of individual variants on a trait by combining these separate genetic variants into a single measure. The...
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| Veröffentlicht in: | Ophthalmology |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5963986/ https://ncbi.nlm.nih.gov/pubmed/29361357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ophtha.2017.12.014 |
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