Angiogenic and pleiotropic effects of VEGF165 and HGF combined gene therapy in a rat model of myocardial infarction

Since development of plasmid gene therapy for therapeutic angiogenesis by J. Isner this approach was an attractive option for ischemic diseases affecting large cohorts of patients. However, first placebo-controlled clinical trials showed its limited efficacy questioning further advance to practice....

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Makarevich, Pavel I., Dergilev, Konstantin V., Tsokolaeva, Zoya I., Boldyreva, Maria A., Shevchenko, Evgeniy K., Gluhanyuk, Evgeny V., Gallinger, Julia O., Menshikov, Mikhail Yu., Parfyonova, Yelena V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963747/
https://ncbi.nlm.nih.gov/pubmed/29787588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197566
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