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Therapeutic Angiogenesis by a “Dynamic Duo”: Simultaneous Expression of HGF and VEGF165 by Novel Bicistronic Plasmid Restores Blood Flow in Ischemic Skeletal Muscle

Therapeutic angiogenesis is a promising strategy for relief of ischemic conditions, and gene delivery was used to stimulate blood vessels’ formation and growth. We have previously shown that intramuscular injection of a mixture containing plasmids encoding vascular endothelial growth factor (VEGF)16...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Slobodkina, Ekaterina, Boldyreva, Maria, Karagyaur, Maxim, Eremichev, Roman, Alexandrushkina, Natalia, Balabanyan, Vadim, Akopyan, Zhanna, Parfyonova, Yelena, Tkachuk, Vsevolod, Makarevich, Pavel
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7766676/
https://ncbi.nlm.nih.gov/pubmed/33353116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12121231
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