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Loss of PTEN in High Grade Advanced Stage Triple Negative Breast Ductal Cancers in African American Women

INTRODUCTION: PTEN is a tumor suppressor gene that inhibits cell proliferation by inhibiting the phosphoinositide 3- kinase (PI3K) signaling pathway. The significance of PTEN mutations resulting in variable PTEN expression and their impact on prognosis of breast cancer is not well established. The o...

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書目詳細資料
發表在:Pathol Res Pract
Main Authors: Khan, Farhan, Esnakula, Ashwini, Ricks-Santi, Luisel J, Zafar, Rabia, Kanaan, Yasmine, Naab, Tammey
格式: Artigo
語言:Inglês
出版: 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963715/
https://ncbi.nlm.nih.gov/pubmed/29653745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prp.2018.03.020
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