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Deletion of the Insulin Receptor in Sensory Neurons Increases Pancreatic Insulin Levels
Insulin is known to have neurotrophic properties and loss of insulin support to sensory neurons may contribute to peripheral diabetic neuropathy (PDN). Here, genetically-modified mice were generated in which peripheral sensory neurons lacked the insulin receptor (SNIRKO mice) to determine whether di...
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| Publicat a: | Exp Neurol |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5963702/ https://ncbi.nlm.nih.gov/pubmed/29649429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2018.04.002 |
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