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Identification of a Small Molecule Activator for AphB, a LysR-Type Virulence Transcriptional Regulator in Vibrio cholerae
AphB is a LysR-type transcriptional regulator (LTTR) that cooperates with a second transcriptional activator, AphA, at the tcpPH promoter to initiate expression of the virulence cascade in Vibrio cholerae. Since it is not yet known whether AphB responds to a natural ligand in V. cholerae that influe...
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| Veröffentlicht in: | Biochemistry |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5963692/ https://ncbi.nlm.nih.gov/pubmed/28640592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00337 |
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