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The Threshold of Toxicological Concern for prenatal developmental toxicity in rats and rabbits

The Threshold Toxicological Concern (TTC) is based on the concept that in absence of experimental data reasonable assurance of safety can be given if exposure is sufficiently low. Using the REACH database the low 5th percentile of the NO(A)EL distribution, for prenatal developmental toxicity (OECD g...

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Publicado en:Regul Toxicol Pharmacol
Autores principales: van Ravenzwaay, B., Jiang, X., Luechtefeld, T., Hartung, T.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963679/
https://ncbi.nlm.nih.gov/pubmed/28645885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yrtph.2017.06.008
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