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The Threshold of Toxicological Concern for prenatal developmental toxicity in rats and rabbits

The Threshold Toxicological Concern (TTC) is based on the concept that in absence of experimental data reasonable assurance of safety can be given if exposure is sufficiently low. Using the REACH database the low 5th percentile of the NO(A)EL distribution, for prenatal developmental toxicity (OECD g...

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Pubblicato in:Regul Toxicol Pharmacol
Autori principali: van Ravenzwaay, B., Jiang, X., Luechtefeld, T., Hartung, T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963679/
https://ncbi.nlm.nih.gov/pubmed/28645885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yrtph.2017.06.008
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