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Ocular Distribution and Pharmacokinetics of Lifitegrast in Pigmented Rabbits and Mass Balance in Beagle Dogs
Purpose: Lifitegrast is approved in the United States for the treatment of dry eye disease (DED). We assessed lifitegrast's ocular distribution/pharmacokinetic profile in rabbits, and (14)C-lifitegrast mass balance/excretion in dogs. Methods: Female pigmented rabbits received a single topical o...
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| Publicado no: | J Ocul Pharmacol Ther |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc., publishers
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5963635/ https://ncbi.nlm.nih.gov/pubmed/29267138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jop.2017.0106 |
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