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Design of Modular Dual Enzyme-Responsive Peptides

Dual enzyme-responsive peptides were synthesized by masking the ε-amine of lysine with various enzyme substrates. Enzymatic cleavage of these sequences unmasked the ε-amine, allowing for further digestion by a second enzyme, which was monitored colorimetrically. This modular peptide design should pr...

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Detalhes bibliográficos
Publicado no:Biopolymers
Main Authors: Boehnke, Natalie, Maynard, Heather D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963286/
https://ncbi.nlm.nih.gov/pubmed/28799649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.23035
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