Effects of the cardiac myosin activator Omecamtiv-mecarbil on severe chronic aortic regurgitation in Wistar rats

BACKGROUND: Aortic regurgitation (AR) is a valvular disease that can lead to systolic heart failure. Treatment options besides cardiac surgery are limited and consequently severe AR is associated with higher mortality and morbidity when not operated. In this investigation, we examined the effects of...

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Publicat a:BMC Cardiovasc Disord
Autors principals: El-Oumeiri, Bachar, Mc Entee, Kathleen, Annoni, Filippo, Herpain, Antoine, Vanden Eynden, Frédéric, Jespers, Pascal, Van Nooten, Guido, van de Borne, Philippe
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963065/
https://ncbi.nlm.nih.gov/pubmed/29783950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12872-018-0831-3
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