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Effects of the cardiac myosin activator Omecamtiv-mecarbil on severe chronic aortic regurgitation in Wistar rats

BACKGROUND: Aortic regurgitation (AR) is a valvular disease that can lead to systolic heart failure. Treatment options besides cardiac surgery are limited and consequently severe AR is associated with higher mortality and morbidity when not operated. In this investigation, we examined the effects of...

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Detalhes bibliográficos
Publicado no:BMC Cardiovasc Disord
Main Authors: El-Oumeiri, Bachar, Mc Entee, Kathleen, Annoni, Filippo, Herpain, Antoine, Vanden Eynden, Frédéric, Jespers, Pascal, Van Nooten, Guido, van de Borne, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963065/
https://ncbi.nlm.nih.gov/pubmed/29783950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12872-018-0831-3
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