The Artemisinin Derivative Artesunate Inhibits Corneal Neovascularization by Inducing ROS-Dependent Apoptosis in Vascular Endothelial Cells

PURPOSE. Without therapeutic intervention, corneal neovascularization rapidly compromises visual acuity, and is a leading cause of blindness. Artesunate was reported to inhibit angiogenesis in tumors, although, the effects of artesunate on nontumor angiogenesis have not been investigated. This study...

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Publicado en:Invest Ophthalmol Vis Sci
Autores principales: Cheng, Rui, Li, Cen, Li, Chaoyang, Wei, Ling, Li, Lei, Zhang, Yang, Yao, Yachao, Gu, Xiaoqiong, Cai, Weibin, Yang, Zhonghan, Ma, Jianxing, Yang, Xia, Gao, Guoquan
Formato: Artigo
Lenguaje:Inglês
Publicado: The Association for Research in Vision and Ophthalmology 2013
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963000/
https://ncbi.nlm.nih.gov/pubmed/23611999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-11068
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