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Loss of Sendai virus C protein leads to accumulation of RIG-I immunostimulatory defective interfering RNA

Retinoic acid inducible gene (RIG-I)-mediated innate immunity plays a pivotal role in defence against virus infections. Previously we have shown that Sendai virus (SeV) defective interfering (DI) RNA functions as an exclusive and potent RIG-I ligand in DI-RNA-rich SeV-Cantell infected cells. To furt...

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Detalhes bibliográficos
Publicado no:J Gen Virol
Main Authors: Sánchez-Aparicio, Maria Teresa, Garcin, Dominique, Rice, Charles M., Kolakofsky, Daniel, García-Sastre, Adolfo, Baum, Alina
Formato: Artigo
Idioma:Inglês
Publicado em: Microbiology Society 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5962894/
https://ncbi.nlm.nih.gov/pubmed/28631605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000815
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