A novel oncolytic herpes simplex virus armed with the carboxyl-terminus of murine MyD116 has enhanced anti-tumour efficacy against human breast cancer cells

Oncolytic herpes simplex virus-1 (oHSV-1) vectors are promising therapeutic agents for cancer. The deletion of the γ34.5 gene eliminates the neurovirulence but attenuates virus replication at the same time. The carboxyl-terminus of protein phosphatase 1 regulatory subunit 15A (also known as MyD116/G...

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Vydáno v:Oncol Lett
Hlavní autoři: Cheng, Lin, Jiang, Hua, Fan, Jingjing, Wang, Jiani, Hu, Pan, Ruan, Ying, Liu, Renbin
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5962873/
https://ncbi.nlm.nih.gov/pubmed/29849789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8247
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