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Inducible high-efficiency CRISPR-Cas9-targeted gene editing and precision base editing in African trypanosomes
The Cas9 endonuclease can be programmed by guide RNA to introduce sequence-specific breaks in genomic DNA. Thus, Cas9-based approaches present a range of novel options for genome manipulation and precision editing. African trypanosomes are parasites that cause lethal human and animal diseases. They...
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| Vydáno v: | Sci Rep |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5962531/ https://ncbi.nlm.nih.gov/pubmed/29785042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26303-w |
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