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Effective discovery of rare variants by pooled target capture sequencing: A comparative analysis with individually indexed target capture sequencing

Identification of all genetic variants associated with complex traits is one of the most important goals in modern human genetics. Genome-wide association studies (GWAS) have been successfully applied to identify common variants, which thus far explain only small portion of heritability. Interests i...

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Dades bibliogràfiques
Publicat a:Mutat Res
Autors principals: Ryu, Seungjin, Han, Jeehae, Norden-Krichmar, Trina M., Schork, Nicholas J., Suh, Yousin
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5962423/
https://ncbi.nlm.nih.gov/pubmed/29677560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2018.03.007
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