Characterization of Lgr6+ Cells as an Enriched Population of Hair Cell Progenitors Compared to Lgr5+ Cells for Hair Cell Generation in the Neonatal Mouse Cochlea

Hair cell (HC) loss is irreversible because only very limited HC regeneration has been observed in the adult mammalian cochlea. Wnt/β-catenin signaling regulates prosensory cell proliferation and differentiation during cochlear development, and Wnt activation promotes the proliferation of Lgr5+ coch...

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Bibliografske podrobnosti
izdano v:Front Mol Neurosci
Main Authors: Zhang, Yanping, Guo, Luo, Lu, Xiaoling, Cheng, Cheng, Sun, Shan, Li, Wen, Zhao, Liping, Lai, Chuijin, Zhang, Shasha, Yu, Chenjie, Tang, Mingliang, Chen, Yan, Chai, Renjie, Li, Huawei
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Neuroscience
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961437/
https://ncbi.nlm.nih.gov/pubmed/29867341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00147
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