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Towards a microparticle-based system for pooled assays of small molecules in cellular contexts

Experimental approaches to the discovery of small molecule probes and drug candidates often use biochemical or cell-based screening of large libraries (>10(5)) of small molecules. Small molecules of interest are tested one at a time in individual wells of a microtiter plate, at a significant cost...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:ACS Chem Biol
Main Authors: Yozwiak, Carrie E., Hirschhorn, Tal, Stockwell, Brent R.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960808/
https://ncbi.nlm.nih.gov/pubmed/29365249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00043
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