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Determination of the subcellular localization and mechanism of action of ferrostatins in suppressing ferroptosis

Ferroptosis is a form of non-apoptotic cell death characterized by the unchecked accumulation of lipid peroxides. Ferrostatin-1 and its analogs (ferrostatins) specifically prevent ferroptosis in multiple contexts, but many aspects of their molecular mechanism of action remain poorly described. Here,...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Gaschler, Michael M., Hu, Fanghao, Feng, Huizhong, Linkermann, Andreas, Min, Wei, Stockwell, Brent R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960802/
https://ncbi.nlm.nih.gov/pubmed/29512999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00199
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