Saccharomyces cerevisiae Differential Functionalization of Presumed ScALT1 and ScALT2 Alanine Transaminases Has Been Driven by Diversification of Pyridoxal Phosphate Interactions

Saccharomyces cerevisiae arose from an interspecies hybridization (allopolyploidiza-tion), followed by Whole Genome Duplication. Diversification analysis of ScAlt1/ScAlt2 indicated that while ScAlt1 is an alanine transaminase, ScAlt2 lost this activity, constituting an example in which one of the me...

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Bibliographische Detailangaben
Veröffentlicht in:Front Microbiol
Hauptverfasser: Rojas-Ortega, Erendira, Aguirre-López, Beatriz, Reyes-Vivas, Horacio, González-Andrade, Martín, Campero-Basaldúa, Jose C., Pardo, Juan P., González, Alicia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960717/
https://ncbi.nlm.nih.gov/pubmed/29867852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.00944
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