Activation of AMPK inhibits inflammatory response during hypoxia and reoxygenation through modulating JNK-mediated NF-κB pathway

BACKGROUND: AMP-activated Protein Kinase (AMPK) is a stress-activated kinase that protects against cardiomyocyte injury during ischemia and reperfusion. c-Jun N-terminal kinase (JNK), a mitogen activated protein kinase, is activated by ischemia and reperfusion. NF-κB is an important transcription fa...

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Publicado en:Metabolism
Main Authors: Chen, Xu, Li, Xuan, Zhang, Wenyan, He, Jie, Xu, Bo, Lei, Bin, Wang, Zhenhua, Cates, Courtney, Rousselle, Thomas, Li, Ji
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960613/
https://ncbi.nlm.nih.gov/pubmed/29526538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2018.03.004
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