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Opposite Interplay Between the Canonical WNT/β-Catenin Pathway and PPAR Gamma: A Potential Therapeutic Target in Gliomas

In gliomas, the canonical Wingless/Int (WNT)/β-catenin pathway is increased while peroxisome proliferator-activated receptor gamma (PPAR-γ) is downregulated. The two systems act in an opposite manner. This review focuses on the interplay between WNT/β-catenin signaling and PPAR-γ and their metabolic...

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Publicat a:Neurosci Bull
Autors principals: Vallée, Alexandre, Lecarpentier, Yves, Guillevin, Rémy, Vallée, Jean-Noël
Format: Artigo
Idioma:Inglês
Publicat: Springer Singapore 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960455/
https://ncbi.nlm.nih.gov/pubmed/29582250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-018-0219-5
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